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Tuesday, October 25, 2016

Stronger muscles lead to stronger brain

study led by the University of Sydney in Australia has found that gradually increasing muscle strength through activities such as weightlifting improves cognitive function. Stronger muscles reduce cognitive impairment in elderly patients. The study was conducted in collaboration with the Centre for Healthy Brain Ageing (CHeBA) at the University of New South Wales and the University of Adelaide. The results have been published in the Journal of American Geriatrics. The trial involved a Study of Mental and Resistance Training (SMART) carried out on patients with mild cognitive impairment (MCI) between 55-68 years old. Patients with MCI have a higher risk of developing dementia and Alzheimer's disease. The findings are particularly significant given the high incidence of dementia and Alzheimer's disease among the aging population. According to the 2016 World Alzheimer Report, 47 million people worldwide have dementia and this number is expected to triple by 2050. In the United States, the figure predicted for people with Alzheimer's disease in 2050 is 13.8 million. Due to the high cost of care for patients with dementia, the World Alzheimer Report recommends moving beyond specialist care. The report suggests a holistic approach that focuses on improving the quality of life for people living with the condition. Seen in this context, a link between physical training and improving brain function might be a step in the right direction. How a disciplined weightlifting schedule can improve cognition The trial looked at progressive resistance training - such as weightlifting - and the functioning of the brain. The study examined 100 older adults living with MCI. "Mild cognitive impairment" refers to older patients who have cognitive difficulties that are noticeable but not significant enough to interfere with their daily activities. Eighty percent of patients diagnosed with MCI develop Alzheimer's disease after approximately 6 years. For the trial, MCI patients were divided into four groups and assigned a range of activities. These included a combination of resistance exercise - including weightlifting - and placebo resistance in the form of seated stretching. Activities also included computerized cognitive training and its placebo equivalent. The cognitive training and placebo activities did not yield cognitive improvements. However, the study did demonstrate a proportional relation between improvement in brain function and improvement in muscle strength. "What we found in this follow-up study is that the improvement in cognition function was related to their muscle strength gains. The stronger people became, the greater the benefit for their brain." Lead author Dr. Yorgi Mavros Previous studies have shown a positive link between physical exercise and cognitive function, but the SMART trial led by Dr. Mavros provides further information on the type, quality, and frequency of exercise needed to get the full cognitive benefits. In the trial, participants did weightlifting sessions twice a week for 6 months, working to at least 80 percent of their peak strength. The weights were gradually increased as participants got stronger, all the while maintaining their peak strength at 80 percent. "The more we can get people doing resistance training like weightlifting, the more likely we are to have a healthier aging population," says Dr. Mavros. "The key, however, is to make sure you are doing it frequently, at least twice a week, and at a high intensity so that you are maximizing your strength gains. This will give you the maximum benefit for your brain." This is also the first time a study has shown a clear causal link between increasing muscle strength and improving brain function in patients over 55 years old who have MCI. Exercise and cognitive function It has been suggested that exercise indirectly helps prevent the onset of Alzheimer's disease and lowers the risk of cognitive impairment. Exercise helps with physiological.

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